2024 – LSBR — Landsteiner Foundation for Blood Transfusion Research

CD8-immunoPET guided lesion selection to improve response to adoptive cell therapy.

Control and triggers of afucosylated IgG responses.

Deciphering the influence of X chromosome inactivation on sex-specific differences in T cell responses to cancer immunotherapy.

Development and validation of artificial blood.

Hijacking of the bone marrow niche by tumor cells: impact on hematopoiesis (HiT-Hema)

Haematopoiesis ─ the process by which all blood and immune cells are generated from Haematopoietic Stem and Progenitor Cells (HSPCs) ─ is maintained by the bone marrow (BM) microenvironment, also termed BM niche. Mesenchymal stromal cells (MSCs) are key elements…

Hijacking of the bone marrow niche by tumor cells: impact on hematopoiesis.

IMMUNE MODULATION THROUGH THE VASCULATURE: The innate immune system talks via the endothelium with the adaptive immune system.

Mapping of the cellular heterogeneity of megakaryocytes in the bone marrow.

Therapeutic small interfering RNAs targeting endothelial von Willebrand factor in von Willebrand disease.

Unravelling the role of bone marrow macrophage and erythroblast interaction in stem cell transplant rejection in β-thalassemia.

Jaar: 2024